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Transcranial Alternating Current Stimulation at the Individual Alpha Frequency Shows Potential Value in Improving Working Memory in Healthy Participants

Neurologia
Imagem de arquivo, ilustrativa — não é do estudo. Cerebelo de embrião de camundongo, em microscopia de fluorescência. NIH · domínio público · Wikimedia Commons

Ensaio clínico randomizadoNível 2 · Nova evidênciaBrain and behavior1 mai 20260 citações

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Resumo original em inglês

O que aconteceu

To clarify the promoting effect of transcranial alternating current stimulation (tACS) at the individual alpha frequency (IAF) of the left posterior parietal cortex (PPC) on working memory (WM) using combined behavioral and electroencephalography (EEG) detection techniques.

This study is a single-blind, randomized, crossover, controlled trial with three groups: the IAF group, the IAF-1 group, and the sham group. WM was assessed using the n-back task, while EEG signals were simultaneously collected. Behavioral and EEG-related indicators pre and post stimulation were compared.

O que encontraram

Compared with pre-stimulation, the average reaction time (RT) in the n-back task significantly decreased (p 0.05). No significant correlations were found in the IAF-1 group or the sham group (p > 0.05).

Por que isso importa

IAF-tACS specially improved the high-load WM performance in healthy participants through increased P300 amplitude in the frontocentral region, which provides a brand-new strategy for precise regulation in the future. Further research are needed to confirm its clinical application.

Resumo publicado sob licença CC BY. A tradução para o português ainda não chegou a este estudo.

O estudo original

Transcranial Alternating Current Stimulation at the Individual Alpha Frequency Shows Potential Value in Improving Working Memory in Healthy Participants

Zhiqiang Wang, Yulan Gao, Menglin Han, Longting Hu, Kangling Wang

Descritores MeSH

  • Memory, Short-Term
  • Parietal Lobe
  • Alpha Rhythm
  • Transcranial Direct Current Stimulation
  • Female
  • Humans
  • Cognitive Enhancement
  • Reaction Time
  • Single-Blind Method
  • Cross-Over Studies

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