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The use of eye-tracking to find objective outcome measures of early intervention strategies for children with autism: A systematic review

Psiquiatria
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Revisão sistemáticaNível 1 · Evidência consolidadaNeuroscience and biobehavioral reviews4 out 20252 citações

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Resumo original em inglês

O que aconteceu

Early intervention strategies are recommended for children with autism to improve cognitive and social communication skills. However, there is a persistent challenge to identify objective outcome measures of intervention efficacy. Eye-tracking (ET) is a safe and well-tolerated technology able to detect differences in visual attention through gaze behavior. This systematic review aims to identify, appraise and summarize the existing literature using ET to track response to early intervention in autism clinical trials.

A comprehensive literature search was conducted in December 2024 in several bibliographic databases, including Medline ALL Ovid, Embase.com, APA PsycInfo Ovid, the Cochrane Library Wiley and PubMed Central. Additionally, we searched trial registries and we performed citation tracking strategies. We retained randomized controlled trials (RCTs) incorporating an ET outcome measure to evaluate the effect of direct, parent-mediated and pharmacological early interventions. Quality was assessed using Risk of Bias 2 and GRADE.

O que encontraram

Out of 1'726 reports screened, eleven articles from nine unique RCTs met inclusion criteria, with overall low-to-moderate risk of bias. Six out of the nine intervention approaches showed improvements in several indices of visual attention measured with different ET paradigms. We also identified 24 RCTs registered with an ET outcome measure yet without published results.

Por que isso importa

ET proved to be a clinically relevant measure sensitive to change in several interventional contexts. However, not all ET paradigms measured change over time reliably, compromising interpretability. Further research is needed to ensure that ET potentially becomes an accessible and accurate tool for widespread adoption in clinical practice.

Resumo publicado sob licença CC BY. A tradução para o português ainda não chegou a este estudo.

O estudo original

The use of eye-tracking to find objective outcome measures of early intervention strategies for children with autism: A systematic review

Chloé Peter, Maria-Paraskevi Antoniou, Evelyne Antonietti, Joana Almeida Osório, Joëlle Rosselet Amoussou, Nadia Chabane, Borja Rodríguez-Herreros

Descritores MeSH

  • Autism Spectrum Disorder
  • Eye-Tracking Technology
  • Outcome Assessment, Health Care
  • Early Intervention, Educational
  • Early Medical Intervention
  • Attention
  • Child
  • Humans

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