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Prosthetic Valve Endocarditis by Acinetobacter baumannii: Case Report and Systematic Descriptive Review

Infectologia
Imagem de arquivo, ilustrativa — não é do estudo. Artéria humana em corte transversal, ao microscópio óptico. Lord of Konrad · CC0 · Wikimedia Commons

Revisão sistemáticaNível 1 · Evidência consolidadaPathogens (Basel, Switzerland)28 mai 20261 citações

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Resumo original em inglês

O que aconteceu

Apart from the description of our case, a PubMed and Embase literature review was conducted up to January 2026 using the terms "A. baumannii" AND ("infective endocarditis" OR "endocarditis" OR "valvular infection"). We included clinical cases of IE caused by A. baumannii published as full-text articles in English.

O que encontraram

After orthopedic osteosynthesis surgery following a femur fracture, our patient developed osteomyelitis by XDR A. baumannii and was treated for a short period of time. Later, prosthetic aortic valve endocarditis was diagnosed. Despite treatment with cefiderocol and eravacycline, she died. An additional 18 clinical cases of IE by A. baumannii were identified from the literature, bringing the total to 19 cases. IE affected prosthetic valves in nine cases, native valves in nine and involved a right atrial mass in one. Twelve cases were caused by MDR or XDR A. baumannii. Mortality occurred more frequently in cases not treated with surgery (9/13, 69%) compared to those treated with surgery (1/6, 16.7%). However, given the very small sample size, these data should be interpreted with caution.

Por que isso importa

This case, together with previously reported observations, highlights the severity of EI by A. baumannii and the need of multidisciplinary management.

Resumo publicado sob licença CC BY. A tradução para o português ainda não chegou a este estudo.

O estudo original

Prosthetic Valve Endocarditis by Acinetobacter baumannii: Case Report and Systematic Descriptive Review

Annabella Salvati, Loredana Alessio, Gloria Trombaccia, Giovanni Cimmino, Marisa De Feo, Fausto Ferraro, Stefania De Pascalis, Nicola Coppola

Descritores MeSH

  • Acinetobacter Infections
  • Endocarditis, Bacterial
  • Heart Valve Prosthesis
  • Prosthesis-Related Infections
  • Acinetobacter baumannii
  • Humans
  • Middle Aged
  • Anti-Bacterial Agents
  • Osteomyelitis
  • Female

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