Prevalência de deficiência auditiva na encefalopatia neonatal por hipóxia-isquemia: revisão sistemática e metanálise

O que aconteceu

This systematic review was undertaken to estimate the overall prevalence of hearing impairment in survivors of neonatal HIE. PubMed, EMBASE, CINAHL, EMCARE and Cochrane databases, mednar (gray literature) were searched till January 2023. Randomized controlled trials and observational studies were included. The main outcome was estimation of overall prevalence of hearing impairment in survivors of HIE. The overall prevalence rate of hearing impairment in cooled infants with HIE was 5% (95% CI: 3-6%) and 3% (95% CI: 1-6%) in the non-cooled infants. The prevalence rate in cooled HIE infants in LMICs was 7% (95% CI: 2-15%) and in HICs was 4% (95% CI: 3-5%). The prevalence rate in non-cooled HIE infants in LMICs was 8% (95% CI: 2-17%) and HICs was 2% (95% CI: 0-4%). These results would be useful for counseling parents, and in acting as benchmark when comparing institutional data, and while monitoring future RCTs testing new interventions in HIE.

Trecho mantido em inglês: a tradução automática não passou na conferência de números.

O que encontraram

A total of 71studies (5821 infants assessed for hearing impairment) were included of which 56 were from high income countries (HIC) and 15 from low- or middle-income countries (LMIC). Overall prevalence rate of hearing impairment in cooled infants was 5% (95% CI: 3-6%, n = 4868) and 3% (95% CI: 1-6%, n = 953) in non-cooled HIE infants. The prevalence rate in cooled HIE infants in LMICs was 7% (95% CI: 2-15%) and in HICs was 4% (95% CI: 3-5%). The prevalence rate in non-cooled HIE infants in LMICs was 8% (95% CI: 2-17%) and HICs was 2% (95% CI: 0-4%).

Trecho mantido em inglês: a tradução automática não passou na conferência de números.

Por que isso importa

Esses resultados seriam úteis para o aconselhamento dos pais e para atuar como referência na comparação de dados institucionais e, ao mesmo tempo, monitorar futuros ECRs testando novas intervenções na EIE. Há necessidade de mais dados das LMICs e padronização do relato de deficiência auditiva.