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O Efeito da Anestesia tópica no Processo de Fonação Durante a Laringoscopia por Imagem Digital de Alta Velocidade em Pacientes com Reflux Laringofaríngeo: Ensaio cruzado randomizado, duplo-cego, controlado com placebo

Gastroenterologia
Imagem de arquivo, ilustrativa — não é do estudo. Pastilha de um circuito integrado Ferranti F111-L ao microscópio. Revaldinho · CC BY 4.0 · Wikimedia Commons

Ensaio clínico randomizadoNível 2 · Nova evidênciaMedicina (Kaunas, Lithuania)5 ago 20260 citações

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Resumo original em inglês

O que aconteceu

High-speed digital imaging (HSDI) is the most advanced method of phonation process analysis. Hoarseness is the most common indication for HSDI, and laryngopharyngeal reflux (LPR) is an etiological cofactor of hoarseness in 50% of cases. Clinical practice in HSDI includes the elective use of topical anesthesia (TA), but without defined recommendations and indications for use, and a potential altering effect of TA on the phonation process has not been unequivocally proven. The aim of this prospective, randomized, double-blind, placebo-controlled study was to examine the effect of TA application on the phonation process by analyzing Voice-Vibratory Assessment with Laryngeal Imaging (VALI) form parameters in subjects with LPR.

A total of 70 volunteer subjects were included in the study; 50 subjects who completed both recording sessions were included in the final analysis. All subjects were recorded in two modalities, with TA application (lidocaine spray 100 mg/mL) and without it, on two consecutive days.

O que encontraram

By evaluating phonation process parameters according to the VALI form, we determined that TA application during HSDI in subjects with LPR was not associated with statistically significant changes in the evaluated phonation process parameters.

Por que isso importa

TA application during HSDI in subjects with LPR was not associated with significant changes in the analyzed phonation process parameters. Further research is needed to determine the benefit of TA in reducing pain and discomfort during examination, weighed against the risk of potentially life-threatening side effects, in order to individualize the approach to each patient.

Resumo publicado sob licença CC BY. A tradução para o português ainda não chegou a este estudo.

O estudo original

The Effect of Topical Anesthesia on the Phonation Process During High-Speed Digital Imaging Laryngoscopy in Patients with Laryngopharyngeal Reflux: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial

Mario Bilić, Juraj Slipac, Matko Prtorić, Maša Mitrović, Iva Botica, Lana Kovač Bilić

Descritores MeSH

  • Laryngopharyngeal Reflux
  • Anesthesia, Local
  • Laryngoscopy
  • Phonation
  • Double-Blind Method
  • Female
  • Hoarseness
  • Humans
  • Cross-Over Studies
  • Lidocaine

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