Household air pollution and blood pressure among adult women participants of the Household Air Pollution Intervention Network Trial: An exposure-response analysis

Resumo original em inglês

O que aconteceu

Exposure to air pollutants, like fine particulate matter (PM2.5), has been linked to higher blood pressure (BP). Few studies have examined this association in biomass-dependent settings. We seek to determine whether high exposure during a 16 month period was associated with an increase in BP among older adult women over the study period and to determine whether short-term increases in exposure were associated with higher coincident blood pressure.

As part of a randomized controlled trial of a free liquefied petroleum gas cookstove and 18-month fuel supply, we measured BP and personal exposure to PM2.5, black carbon (BC), and carbon monoxide (CO) on 368 adult women (mean age 52) in four countries (Rwanda, Peru, Guatemala, and India). We considered short- and long-term associations, the latter measured by change in BP and the former in mixed models of repeated measures.

The study is registered with ClinicalTrials.gov (NCT02944682) and funded by the U.S. National Institutes of Health (1UM1HL134590) in collaboration with the Bill & Melinda Gates Foundation (OPP1131279).

O que encontraram

We found an association between short-term exposure and both systolic and diastolic BP. The highest quartile of BC was associated with a 2 mmHg increase compared to the referent group (p = 0.03). We also found a positive association with PM2.5, where the highest quartile had a 1.6 mmHg increase in SBP versus the referent group (p = 0.05). We found no association with long-term exposure, nor between CO and BP.

Por que isso importa

In settings where HAP dominates air pollution exposure, we found short-term exposure to BC and PM2.5 associated with increased BP, consistent with past literature. The lack of long-term associations may have been due to insufficient follow-up.

Resumo publicado sob licença CC BY. A tradução para o português ainda não chegou a este estudo.