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ESGO Consensus Statement on endometrial cancer prevention, risk reduction strategies, and management of women with Lynch syndrome

Oncologia
Imagem de arquivo, ilustrativa — não é do estudo. Células HeLa em cultura, em microscopia de fluorescência. NIH · domínio público · Wikimedia Commons

Diretriz clínicaNível 1 · Evidência consolidadaEuropean journal of cancer (Oxford, England : 1990)15 abr 20264 citações

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Resumo original em inglês

O que aconteceu

Lynch syndrome (LS) is a hereditary condition associated with an increased susceptibility to developing cancer, primarily colorectal and gynaecological cancer (endometrial cancer and ovarian cancer). The European Society of Gynaecological Oncology (ESGO) nominated fifteen practicing multidisciplinary clinicians with expertise in this field and ten gynaecological and oncological fellows with interest in the topics to develop evidence-based statements, sharing and standardizing the management of LS carriers. Published evidence was integrated with clinical experience to reach Consensus Statements through anonymous voting. In this Consensus, thirty-one statements based on the best available evidence and expert agreement are offered. They focused on genetic and cancer risk counseling principles, screening procedures, risk-reducing surgical and medical strategies, and address emerging topics such as reproductive issues for LS carriers, which are important in current practice. This manuscript reports the Statements that reached a consensus, their voting results, and a summary of supporting evidence.

Resumo publicado sob licença CC BY. A tradução para o português ainda não chegou a este estudo.

O estudo original

ESGO Consensus Statement on endometrial cancer prevention, risk reduction strategies, and management of women with Lynch syndrome

Claudia Marchetti, Murat Gultekin, Carolina Maria Sassu, François Planchamp, Laura Burney Ellis, Sarah J Bowden, Vasilis Theodoulidis, Vesna Kesic, Beyhan Ataseven, Giovanni Scambia et al.

Descritores MeSH

  • Colorectal Neoplasms, Hereditary Nonpolyposis
  • Endometrial Neoplasms
  • Risk Reduction Behavior
  • Genetic Testing
  • Humans
  • Consensus
  • Genetic Predisposition to Disease
  • Female
  • Genetic Counseling

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