Eletroacupuntura combinada com Terapia Comportamental Cognitiva para Insônia Alívia a Comorbidade Insônia-Ansiedade em Pacientes com Câncer Ginecológico Quimioterapia em andamento: Um Ensaio Controlado Randomizado

Resumo original em inglês

O que aconteceu

Insomnia and anxiety affect many gynecological cancer patients on chemotherapy, and non-pharmacological options are limited. This randomized trial examined whether adding electroacupuncture (EA) to cognitive behavioral therapy for insomnia (CBT-I) improves both conditions. Seventy-six patients received EA + CBT-I or sham EA + CBT-I for 4 weeks. Outcomes included sleep quality (PSQI), insomnia severity (AIS), anxiety (HAMA), objective sleep parameters, and overall response rate. At Week 4, the EA group showed a greater reduction in PSQI global score (mean difference in change from baseline: -3.11, 95% CI: -4.11 to -2.11, p p = 0.010) and HAMA ≤ 14 (92.1% vs. 65.8%, p = 0.005). Deep sleep (p = 0.001), REM sleep (p = 0.045), and sleep score (p = 0.008) also increased more with EA group. The overall response rate was higher with EA (92.1% vs. 71.1%, p = 0.016). No serious adverse events occurred. These findings suggest that adding EA to CBT-I improves sleep and anxiety in this population, with a favorable safety profile.

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