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Behavioral Modeling and its Association with PrEP and ART Use in Ugandan HIV-Serodifferent Couples

Infectologia
Imagem de arquivo, ilustrativa — não é do estudo. Linfócito T infectado pelo HIV, ao microscópio eletrônico de varredura (colorizado). NIAID · CC BY 2.0 · Wikimedia Commons

Ensaio clínico randomizadoNível 2 · Nova evidênciaAIDS and behavior16 fev 20242 citações

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Resumo original em inglês

O que aconteceu

Integrating Pre-Exposure Prophylaxis (PrEP) delivery into Antiretroviral Therapy (ART) programs bridges the Human Immunodeficiency Virus (HIV) prevention gap for HIV-serodifferent couples prior to the partner living with HIV achieving viral suppression. Behavioral modeling is one mechanism that could explain health-related behavior among couples, including those using antiretroviral medications, but few tools exist to measure the extent to which behavior is modeled. Using a longitudinal observational design nested within a cluster randomized trial, this study examined the factor structure and assessed the internal consistency of a novel 24-item, four-point Likert-type scale to measure behavioral modeling and the association of behavioral modeling with medication-taking behaviors among heterosexual, cis-gender HIV-serodifferent couples. In 149 couples enrolled for research, a five-factor model provided the best statistical and conceptual fit, including attention to partner behavior, collective action, role modeling, motivation, and relationship quality. Behavioral modeling was associated with medication-taking behaviors among members of serodifferent couples. Partner modeling of ART/PrEP taking could be an important target for assessment and intervention in HIV prevention programs for HIV serodifferent couples.

Resumo publicado sob licença CC BY. A tradução para o português ainda não chegou a este estudo.

O estudo original

Behavioral Modeling and its Association with PrEP and ART Use in Ugandan HIV-Serodifferent Couples

Liying Wang, Timothy R Muwonge, Jane M Simoni, Florence Nambi, Lylianne Nakabugo, Joseph Kibuuka, Dorothy Thomas, Ingrid T Katz, Erika Feutz, Katherine K Thomas et al.

Descritores MeSH

  • Pre-Exposure Prophylaxis
  • Sexual Partners
  • HIV Infections
  • Longitudinal Studies
  • Male
  • Sexual Behavior
  • Medication Adherence
  • Uganda
  • Adult
  • Drug Monitoring

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