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Aplicação de um Programa de Psicoterapia Exploratória Baseada em TDB para Sintomas Relacionados ao Suicídio em Ambulatórios Chineses com Transtornos Afetivos

Psiquiatria
Imagem de arquivo, ilustrativa — não é do estudo. Tratografia por ressonância magnética: tratos de substância branca no cérebro de um camundongo. NIH · domínio público · Wikimedia Commons

Ensaio clínico randomizadoNível 2 · Nova evidênciaBrain and behavior1 out 20260 citações

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Resumo original em inglês

O que aconteceu

This exploratory pilot study aimed to examine the potential effects of a shortened, individually delivered dialectical behavior therapy (DBT)‐based intervention added to pharmacotherapy on suicide‐related outcomes among Chinese outpatients with affective disorders

Twenty‐one participants recruited from the psychiatric outpatient clinics of the First Affiliated Hospital, School of Medicine, Zhejiang University, were randomly assigned to two groups. Participants in the research group received pharmacotherapy plus a shortened, individually delivered DBT‐based intervention, whereas those in the control group received pharmacotherapy alone. Participants completed baseline assessments, 12 weeks of treatment, and 12 weeks of follow‐up, with assessments performed every 4 weeks. Outcomes included suicide risk or severity, depression, anxiety, and hopelessness assessed using self‐report scales

O que encontraram

After adjustment for baseline values using repeated‐measures analysis of covariance (RM‐ANCOVA), the between‐group effect on suicide risk showed a marginal trend favoring the DBT‐based psychotherapy group, but did not reach conventional statistical significance ( F = 4.26, p = 0.054). The time effect ( F = 0.234, p = 0.965) and time‐by‐group interaction ( F = 1.306, p = 0.261) for suicide risk were not statistically significant. Depressive symptoms showed a significant time effect across the follow‐up period, whereas most suicide‐related and hopelessness outcomes were not statistically significant. These findings should be interpreted as preliminary because of the small sample size and baseline imbalance

Por que isso importa

The results provided preliminary pilot evidence that a shortened DBT‐based intervention may be feasible and potentially beneficial as an adjunct to pharmacotherapy in this clinical population. However, the primary suicide‐risk outcome did not show a statistically significant between‐group effect. Larger adequately powered trials with baseline‐adjusted analyses and more comprehensive outcome assessment are needed before firm conclusions can be drawn

Resumo publicado sob licença CC BY. A tradução para o português ainda não chegou a este estudo.

O estudo original

Application of an Exploratory DBT-Based Psychotherapy Program for Suicide-Related Symptoms in Chinese Outpatients With Affective Disorders

Chanchan Hu, Jingkai Chen, Zhong Wang, Xiaoyi Zhou, Yujin Yang, Shuguang Li, Ruili Zhang, Jianbo Lai, Jianbo Hu, Manli Huang et al.

Descritores MeSH

  • Mood Disorders
  • Suicide Prevention
  • Dialectical Behavior Therapy
  • Anxiety
  • China
  • Combined Modality Therapy
  • Depression
  • Female
  • Humans
  • Male

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