Anti-erosive effect of silver diamine fluoride against enamel erosion: An in situ study

Resumo original em inglês

O que aconteceu

To investigate anti-erosive effect of silver diamine fluoride (SDF) against enamel erosion and assessed associated color change.

This three-phase crossover in situ study compared anti-erosive effect of SDF and stannous chloride/amine fluoride/sodium fluoride mouthrinse (SNF) against distilled water (DW, control), while evaluating enamel color changes. Fifteen adults (27-35 years) wore palatal appliances with four-enamel blocks per phase, alternating 14-day intervention periods (weekly 38% SDF [255,000 ppm Ag, 44,800 ppm F], daily SNF mouthrinse [800 ppm Sn, 500 ppm F], or weekly DW) separated by 7-day washouts. Appliances were exposed with five 2 min extraoral erosive challenges (citric acid, pH 3.2) daily. Post-intervention analyses included salivary pellicle morphology (atomic force microscopy, AFM), enamel surface integrity (scanning electron microscopy, SEM), elemental composition (energy-dispersive X-ray spectroscopy, EDS), crystal structure (X-ray diffraction, XRD), surface microhardness loss (hardness tester), surface loss (optical profilometry), and color change (spectrophotometry).

O que encontraram

AFM revealed altered pellicle morphology in SDF and SNF groups. SEM demonstrated reduced enamel erosion in SDF and SNF versus DW. EDS confirmed Ag+ deposition in SDF and Sn2+ in SNF. XRD identified fluorapatite in SDF and SNF groups. SDF showed the lowest surface microhardness loss (21.7±1.0%) and surface loss (µm) (2.7±0.6), followed by SNF (30.0±1.1%; 3.2±0.7), and DW (42.4±1.0%; 5.4±0.8) (p<0.001). However, SDF caused greatest color change (ΔE00=6.6±2.1), followed by SNF (ΔE00=5.8±1.0), and DW (ΔE00=3.6±1.7) (p<0.001).

Por que isso importa

Weekly SDF application demonstrated superior erosion resistance compared to daily SNF, likely attributed to silver-fluoride-induced fluorapatite crystallization and pellicle structural reinforcement. However, enamel staining is an esthetic trade-off.

Resumo publicado sob licença CC BY. A tradução para o português ainda não chegou a este estudo.