Alterações longitudinais na qualidade de vida entre os pacientes que recebem suporte nutricional domiciliar: revisão sistemática e metanálise

Resumo original em inglês

O que aconteceu

Home nutrition support (HNS), including home enteral nutrition (HEN) and home parenteral nutrition (HPN), is widely used in patients who cannot meet their nutritional requirements through oral intake alone. However, longitudinal changes in quality of life (QoL) following HNS have not been systematically synthesized.

PubMed, Embase, Web of Science, CNKI, Wang fang, VIP, SinoMed, and the Cochrane Library were searched from inception to June 2026 to identify longitudinal studies evaluating QoL among adults receiving HNS. The methodological quality of included studies was assessed. QoL changes at 1, 2, 3, 4, and 6 months after HNS initiation were compared with baseline and synthesized using meta-analysis.

O que encontraram

Eighteen studies were included. The pooled SMDs at 1, 2, 3, 4, and 6 months were 0.29, 0.54, 0.64, 0.61, and 0.09, respectively. The 1 to 4 month estimates were statistically significant, while the 6 month estimate was not (95% CI: -0.20 to 0.38). Descriptive evidence from three non-pooled studies suggested possible improvements in the physical and psychosocial domains of QoL.

Por que isso importa

Patients receiving HNS experienced statistically significant improvements from baseline in QoL during the first 1-4 months, with the largest pooled estimates observed between 2 and 4 months. The improvement was smaller at 6 months and did not reach statistical significance. The pattern suggests a descriptive temporal trend, though the studies contributing to each time point differed. Further longitudinal studies with longer follow-up are needed to clarify the long-term changes of QoL among patients receiving HNS.Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD420261414696, identifier: CRD420261414696.

Resumo publicado sob licença CC BY. A tradução para o português ainda não chegou a este estudo.